I'm going to start by stating that I have never used this method. I don't catch skunks in my country. I have attended demos by well experience ADC guys and have listened to their methods. I am certain that a large dose of acetone into the lungs will rapidly dispatch a skunk. Here are a few kinks in the method; it flat sounds bad. If you miss the lungs what happens? Can you accurately diagram the anatomy of a skunk and show the "trajectory” of a needle necessary to hit and remain in the lungs and from different angles and on different size skunks? Considering the above comments / questions do you now see some real problems with an untrained / inexperienced trapper using this or any other method without proper training?
I am not wanting to pick on you, but rather use your posts as a sounding board and possibly / hopefully provide some focus points for thought. Dispatching animals is or should be a major concern for every hunter, trapper etc. We should use methods that we are comfortable and proficient with...this is our obligation to the animals and promise to those that grant us the privilege to hunt / trap.
One last point, again only as an example, acetone is so dang different chemically from mineral spirits I don't know where to begin. I will say that, from the stand point of chemistry, they should never be substituted one for the other for just about any purpose short of fueling a fire.